Casa Sirena

Featured
Type
8 Bedrooms
Entire Place
Accommodation
16 Guests
Bedrooms
8 Bedrooms
9 Beds
Bathroom
10 Full

About this listing

Great for large groups!

This five-story Spanish colonial style home, 80 years in the making, has been carefully restored to preserve its unique heritage while enjoying modern amenities. Formerly a renowned Boutique Hotel, Casa Sirena is now a Private Residence and Vacation Rental

Visit Casa Sirena for a Downtown Hacienda Style Experience

Dreaming of a tranquil escape to the island of Isla Mujeres? Look no further than Casa Sirena! Tucked away in a quiet neighborhood, this wonderful vacation rental is just steps away from the ferry terminal, is located in downtown “Centroโ€ which is filled with vibrant shops, incredible restaurants, and the finest white sand beaches Mexico has to offer.

Whether you’re planning an escape for a smaller group, or a larger group for a destination wedding, family reunion, etc Casa Sirena can accommodate up to 18 overnight guests! Look no further โ€“ Casa Sirena is the place to gather!

First Floor

  • Bedroom 8 – Sofa bed The Double room is complete with ensuite bath and is located on the ground floor, perfect for those with mobility concerns with easy access to the living/dining area, kitchen, lush courtyard and plunge pool.Sleeps 2
  • Bedroom 9 : The Futon room is complete with ensuite bath and is located on the ground floor, perfect for setting up a massage table, or for those with mobility concerns. This room has easy access to the living/dining area, kitchen, lush courtyard and plunge pool.  Sleeps 1 *Advance notice required

Second Floor

  • Bedroom 1 -King Room with Balcony Located on the 2nd floor this room has a King bed which can convert into two single beds, a large private balcony, view of courtyard and ensuite bath. Sleeps 2
  • Bedroom 2 – Queen bed This room is located on the 2nd floor and has a courtyard garden view and ensuite bath. Sleeps 2
  • Bedroom 3 – King bed, Queen bed Located on the 2nd floor this sea view two room suite has a King bed that can be converted into two single beds, a Queen bed, balcony and ensuite bath. Sleeps 4

Third Floor

  • Bedroom 4 – King bed This room is located on the 3rd floor this room has a King bed which can convert into two single beds, balcony with city view and ensuite bath. Sleeps 2
  • Bedroom 5 – Queen bed Located on the 3rd floor, this room has a Queen bed, balcony with courtyard view and ensuite bath. Sleeps 2
  • Bedroom 6 – Queen bed This room is located on the 3rd floor, balcony with sea view and ensuite bath. This room can become a suite, please see description below*.  Sleeps 2
  • Bedroom 7 – Double bed Combined with Room 6, and located on the 3rd floor, this sea view two room suite has a Queen bed, a Single bed, shared  balcony and ensuite bath. Sleeps 3 

Casa Sirena Bedroom Tour

Things to Note

Guests will be greeted by the staff of Casa Sirena.
Laundry service is available

Cleaning Policy/Frequency

Daily Housekeeping (except Sundays)

Have you read this blog post about why Casa Sirena is the best 9 bedroom villa in centro?

Video

Availability

Custom Period Prices

Start DateEnd DatePrice
2025-01-052025-05-311200
2025-06-012025-08-311100
2025-09-012025-11-231000
2025-11-242025-11-301300
2025-12-012025-12-211000
2025-12-222026-01-041500
2026-01-052026-05-311200
2026-06-012026-08-311100
2026-09-012026-11-231000
2026-11-242026-11-301300
2026-12-012026-12-211000
2026-12-222027-01-041500

Prices

Terms

Cancellation Policy

Additional rules information

Rates and availability subject to change without notice before confirmed with deposit. Minimum age of primary renter is 21 years

Details

3:00 PM
10:00 AM

Accommodation

Bedroom 1
1 King Bed
2 Guests
Bedroom 2
1 Queen Bed
2 Guests
Bedroom 3
2 King and Queen Beds
3 Guests
Bedroom 4
1 King Bed
2 Guests
Bedroom 5
1 Queen Bed
2 Guests
Bedroom 6
1 Queen Bed
2 Guests
Bedroom 7
1 Double Bed
2 Guests
Bedroom 8
1 Sofa Bed
1 Guests

Features

Amenities

Great for big groups

June 13, 2026

Rooms were cleaned everyday and tidied to an extreme professional standard. Host was friendly and responsive with any maintenance requests. Walking distance to everything downtown. Great for big groups. Would 100% recommend this location for any destination event or large group trip.

steven r.

Highly recommend Casa Sirena

May 15, 2026

We had an incredible stay at Casa Sirena. The home is absolutely beautiful, and every room is spacious and comfortable—perfect for a large group like ours. From the moment we arrived, the experience was top-notch. Chris (owner) and Juan (manager) run a first-class operation. We were welcomed with fresh guacamole and margaritas waiting for us, which set the tone for the entire trip. The staff went above and beyond every day—preparing coffee each morning and keeping the house spotless from top to bottom. It truly felt like a luxury experience. The location couldn’t have been better. It’s centrally located, making it an easy walk to Playa Norte and Hidalgo Street, so you’re close to everything without needing transportation. One of our favorite features was the spacious fourth floor, which has an additional splash pool and bar. It was the perfect spot to watch both sunrise and sunset, and we found ourselves up there every evening for happy hour. I was initially concerned the pool might be too small for our group of 12, but it handled all of us comfortably when we wanted to cool off and relax. Highly recommend Casa Sirena—we would absolutely stay here again.

Todd H

absolutely delightful!

April 19, 2026

Our stay at Casa Sirena was absolutely delightful! My extended family of 5 couples plus 2 singles thoroughly enjoyed the privacy of each one’s own very quiet bedroom and bathroom, along with all the other amenities Casa offers. Casa staff was very attentive and helpful, and we especially appreciated Edmundo’s efforts in keeping us all well-stocked with the best Margaritas in Mexico! I can’t say enough about Casa property manager, Juan – he truly was the finest concierge we’ve ever encountered. He not only led us poor lost souls to Casa from the ferry dock, but he catered to every whim we had throughout our stay. My family would definitely stay here again! Gracias Chris!

Margaret S.

Would definitely stay again!

April 7, 2026

Casa Sirena was a fantastic stay—clean, comfortable, and had everything we needed. The rooms are spacious with private bathrooms, which made it feel extra relaxing. The rooftop deck is a highlight, and having two pools is a big bonus. The staff were wonderful and welcoming, and the location is perfect—close to everything but still feels like a retreat. Would definitely stay again!

Connie Ewen

Would absolutely stay here again.

January 20, 2026

Central location close to all the downtown restaurants and under 15 minutes walking to Playa Norte. Recommend renting golf carts if you plan to visit anywhere in the central or southern part of the island. Friendly host with excellent communication and hospitality. The property concierge was responsive and very helpful. Housekeeping staff onsite daily for cleaning. Spacious bedrooms with plenty of bathrooms. Rooftop deck with 360 views – can see the sunrise and sunset from up there. Would absolutely stay here again.

Hemang K.

Really recommend

November 26, 2025

Super cool experience really recommend beautiful views with everything being super close to the property

Alvaro Ramirez

My son proposed to his fiancé up top at sunset and it was gorgeous.

November 26, 2025

This place is absolutely beautiful, the views especially at sunset from roof are breathtaking! My son proposed to his fiancé up top at sunset and it was gorgeous. Rooms are clean and comfy . You have to stay here . The island is a must !

Crystal

Beautiful place, spotless, comfortable

November 26, 2025

Beautiful place, spotless, comfortable, and even better than the photos. The views were unbelievable, especially at sunset, and the ocean breeze made every moment feel like a true getaway.

Jesse Chalk

Perfect location. Excellent accommodation

August 19, 2025

Perfect place for us to celebrate my brother in law’s birthday. All of the rooms were very spacious, clean and comfortable. The staff was there every day to straighten things up. The downstairs kitchen ,living room and outdoor area with a pool was great for gathering in the morning and evening for conversation meals and planning activities. The upstairs rooftop deck was perfect for late afternoon and early evening cocktails watching the sun set. The location was great. A short walk to bars, stores and restaurants. Overall a perfect place to spend a vacation. Already booked for next year.

JD E

60th Birthday

March 20, 2025

Thank you Chris and Kirk.I had 60th birthday with alot of fun friends Best birthday ever, accommodations where outstanding, jaun the manager went above and beyond for us. The staff was 5 star. We Will all be back next year.

P.S fell in love with isla Mujeres.

Paul L
$1200.00
/ per night (Seasonal Rates)
$
$
$
$
$
$
$
$
$

Casa Sirena

$1200.00
/ per night (Seasonal Rates)